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Symbol
Name
ID
Hcn4
hyperpolarization-activated, cyclic nucleotide-gated K+ 4
MGI:1298209
Phenotype annotations related to nervous system
Darker colors indicate more annotations
Human Phenotypes
EEG with spike-wave complexes (>3.5 Hz)
Echolalia
Phonic tics
Aggressive behavior
Compulsive behaviors
Motor tics
Attention deficit hyperactivity disorder
Self-mutilation
Sleep abnormality
Bilateral tonic-clonic seizure
Generalized non-motor (absence) seizure
Generalized myoclonic seizure
Disease(s) Associated with HCN4
Gilles de la Tourette syndrome
idiopathic generalized epilepsy

Mouse Phenotypes
abnormal olfactory bulb glomerular layer morphology
small olfactory bulb
abnormal nervous system electrophysiology
Availability Mouse Genotype
Hcn4tm1Nnka/Hcn4+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory